BIOCHEMICAL AND BIOMECHANICAL SUBSTANTIATION OF REPARATIVE REGENERATION OF INTERVERTEBRAL DISCS IN PATIENTS WITH DEGENERATIVE DISC DISEASES
نویسندگان
چکیده
منابع مشابه
Cytokines in the Intervertebral Discs of Patients Undergoing Lumbar Discectomy and Fusion for Degenerative Disc Disease
Study Design: Prospective case series. Objective: Determine whether particular inflammatory cytokines are present within the painful degenerative disc and if so, whether these may serve as biomarkers for post-operative improvement. Summary of Background Data: Low back and leg pain are common problems that may arise as sequelae of degenerative disc disease of the lumbar spine. The production of ...
متن کاملBiomechanical disc culture system: feasibility study using rat intervertebral discs.
A small-scale biomechanical disc culture system was designed to stimulate intervertebral disc (IVD) 'motion segment' in culture environment with load-controlled compression and combined load (compression+shear). After 7 days of diurnal mechanical loading, cell viability of discs stimulated with static compression load (0.25 MPa) and static combined load (compression (0.25 MPa)+shear (1.5N)) wer...
متن کاملThe biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc
INTRODUCTION In the present study, we sought to quantify and contrast the secretome and biomechanical properties of the non-chondrodystrophic (NCD) and chondrodystrophic (CD) canine intervertebral disc (IVD) nucleus pulposus (NP). METHODS We used iTRAQ proteomic methods to quantify the secretome of both CD and NCD NP. Differential levels of proteins detected were further verified using immuno...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Eastern Ukrainian Medical Journal
سال: 2020
ISSN: 2664-4231,2663-5909
DOI: 10.21272/eumj.2020;8(3):249-254